Experiences

  • Research Scientist,Bioinformatics & Computational Biology
    University of Virginia,Charlottesville
    Identifying splicing alterations in patients diagnosed with AML
  • Intern (Predictive Sciences)
    Bristol Myers Squibb,Cambridge,MA (Remote)
    •Reproduced and applied an existing tumor microenvironment (TME) subtype method to pancreatic cancer data from TCGA
					  •Modified the existing Tumor micro environment (TME) subtype classification approach for solid tumors
					  •Developed an R shiny application implementing existing and improved TME classification method on tumor data
  • Bioinformatics Analyst
    University of Virginia,Charlottesville
    Contributed to the study that identified genetic basis of disease relapse in AML
  • Bioinformatics Analyst
    Weill Cornell Medicine,New York
    Identified DNA methylation and transcriptional changes in patients diagnosed and relapsed with acute myeloid leukemia (AML) and MDS
  • Bioinformatician
    Indiana University - Purdue University(IUPUI), Indianapolis
    •Analyzed and identified mutational landscape of RNA binding proteins across 6000 cancer genomics constituting 26 cancer types from TCGA consortium.
•Identified splicing alternations contributing to endocrine resistance in breast cancer cell lines in collaborative research with IU School of Medicine.
•Curated RNA binding proteins and their known functional characteristics identified in humans to construct a database useful for researchers in the field

Education

  • Doctor of Philosophy(PhD)
    University of Virginia,Charlottesville,Virginia
    					  •Identified clinical subgroups in older adults diagnosed with AML enrolled in ECOG-ACRIN’s clinical trial
                      •Identified transcriptional signatures contributing to leukemogenesis in the older adults diagnosed with AML enrolled in ECOG-ACRIN’s clinical trial
					  •Developing an XGBoost-based prognostic model utilizing DNA methylation data (bisulfite sequencing) in older adults diagnosed with (AML) enrolled in ECOG-ACRIN’s clinical trial
					  •Identified transcriptional and DNA methylation changes contributing to myelodysplastic syndrome upon tet2 knockdown in a zebrafish model
  • Masters of Technology(M.Tech)
    University of Hyderabad,Hyderabad,India
    Thesis: Integrating disease-gene and protein-protein interactions to identify candidate genes for Psoriasis using network theory
  • Bachelor of Technology(B.Tech)
    Sreenidhi Institute of Science and Technology (JNTU affiliated),Hyderabad,India
     
     
     
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